Vasopressor meets vasodepressor: The AT1–B2 receptor heterodimer
نویسندگان
چکیده
منابع مشابه
Characterization of murine vasopressor and vasodepressor prostaglandin E(2) receptors.
Four E-prostanoid (EP) receptors, designated EP(1), EP(2), EP(3), and EP(4), mediate the cellular effects of prostaglandin E(2) (PGE(2)). The present studies pharmacologically characterize the vasopressor and vasodepressor EP receptors in wild-type mice (EP(2)(+/+) mice) and mice with targeted disruption of the EP(2) receptor (EP(2)(-/-) mice). Mean arterial pressure (MAP) was measured via a ca...
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The precise role of nitric oxide (NO) in hypertension is still not fully understood, although this vasodilator system represents the main counterbalance of major pressor systems. The aim of our study was to determine the contributions of superoxide anions, the renin-angiotensin system (RAS), the sympathetic nervous system (SNS) and NO to the maintenance of blood pressure (BP) in Prague heredita...
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There have been few reports of vasodepressor carotid sinus syncope, as opposed to the cardioinhibitory type, and no definitive treatment has been described. A 58 year old man developed episodes of syncope after surgery and radiotherapy for a laryngeal tumour. The episodes were characterised by hypotension, sharp pain in the right neck, dizziness, and bradycardia. A temporary pacemaker failed to...
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Vasodepressor syncope is characterized hemodynamically by a sudden fall in total peripheral resistance with little associated change in cardiac output. The failure of the cardiac output to compensate for the fall in peripheral resistance is a striking feature of the fainting reaction. Possible explanations for this phenomenon are the presence of neurogenie myocardial inhibition or markedly limi...
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Vasodepressor syncope is the fulminant expression of the behavioral disorder "Blood-Injury Phobia". Vasodepressor syncope or the "common faint" is characterized by a diphasic autonomic hyperactivity that begins with anxiety and leads to a transient loss of consciousness. Recognition of the behavioral etiology of this disorder suggests the possibility of prevention through psychotherapy. Underst...
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ژورنال
عنوان ژورنال: Biochemical Pharmacology
سال: 2014
ISSN: 0006-2952
DOI: 10.1016/j.bcp.2014.01.019